The reference site for Lisinopril

Lisinopril is a drug of the angiotensin-converting enzyme (ACE) inhibitor class used primarily in treatment of high blood pressure, heart failure, and after heart attacks. It is also used for preventing kidney and eye complications in people with diabetes. Its indications, contraindications, and side effects are as those for all ACE inhibitors.

WHAT IS Lisinopril?

Lisinopril is in a class of drugs called angiotensin-converting-enzyme (ACE) inhibitors.

This medicine is used to lower blood pressure, to treat congestive heart failure and to improve the survival rate after a heart attack. It decreases certain chemicals that tighten the blood vessels, (in other words lisinopril dilates the blood vessels) so blood flows more smoothly and the heart can pump blood more efficiently.

Interestingly, lisinopril and other ACE inhibitors were developed from the venom of a poisonous Brazilian snake.

This medication was first developed by Merck & Co., and is marketed worldwide by Merck with the brand name Prinivil® and by AstraZeneca with the brand name Zestril®. In Australia it is marketed by AlphaPharm with the brand name Lisodur®. In most countries generics are available.

moleculesBrand Name(s): Prinivil; Zestril
CAS nº: 83915-83-7
(Lyse in’ oh pril)

Product Info

The sections below will provide you with more specific information and guidelines related to fluoxetine and its correct use. Please read them carefully.

FDA Information

Lisinopril was approved by the US FDA on 24th of November 1995.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

This medication is in a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. Angiotensin is a chemical that is made by the body continuously, and it works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently.

Lisinopril is used alone or in combination with other medications to treat high blood pressure.

Additionally, it is also used in combination with other medications to treat heart failure and has been administered as a means of improving the survival rate after a heart attack.

Other uses for this medicine

This medication may also be used to help protect the kidneys from damage caused by diabetes.

However, it is important that you consult your doctor about the possible risks of using this drug for your particular condition as this can vary from patient to patient.

Dosage and using this medicine

For the treatment of high blood pressure, the initial starting dose is usually 10 milligrams taken once a day. Your doctor will increase the dosage until your blood pressure is under control. The long-term dosage usually ranges from 20 to 40 milligrams a day, taken in a single dose.

For heart attacks, the usual dose is 5 milligrams within the first 24 hours after a heart attack, then 5 milligrams 24 hours later, 10 milligrams 48 hours later and, finally, 10 milligrams once a day for 6 weeks.

Take lisinopril exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Each dose should be taken with a full glass of water, and even with or without food.

Do not stop taking lisinopril without first consulting to your doctor. If you stop taking this medication suddenly, your condition could deteriorate.

What special precautions should I follow?

It is strongly advised that you inform your doctor and pharmacist if you are allergic to lisinopril, enalapril (Vasotec®), benazepril (Lotensin®), captopril (Capoten®), fosinopril (Monopril®), moexipril (Univasc®), perindopril (Aceon®), quinapril (Accupril®), ramipril (Altace®), trandolapril (Mavik®), or any other drugs.

Additionally, please tell your doctor and pharmacist what prescription and non-prescription medications you are taking, especially diuretics (‘water pills’), lithium (Eskalith® and Lithobid®), other medications for high blood pressure, potassium supplements, salt substitutes and vitamins.

Also let your doctor know if you have or have ever had heart or kidney disease, diabetes, or angioedema, a condition that causes hives, difficulty breathing, and painful swelling of the face, lips, throat, tongue, hands, or feet.

Lisinopril may pass into breast milk and harm newborn infants, so please tell your doctor if you are breast-feeding.

If you are having surgery, including dental surgery, it is advised that you tell the doctor or dentist that you are taking lisinopril.

As with the majority of medications, alcohol may increase drowsiness and dizziness while you are taking lisinopril, so please use it cautiously.

What should I do if I forget a dose?

If you have forgotten to take a dose of lisinopril, take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled one.

Never take a double dose of this medication.

What side effects can this medication cause?

Possible side effects from fluoxetine use may include:

upset stomach
weakness or tiredness
excitement or anxiety
dry mouth
skin more sensitive to sunlight than usual
changes in appetite or weight

Tell your doctor if any of these symptoms are severe or do not go away:

difficulty urinating
frequent urination
blurred vision
changes in sex drive or ability
excessive sweating

If you experience any of the following symptoms, call your doctor immediately:

jaw, neck, and back muscle spasms
slow or difficult speech
shuffling when walking
persistent, fine tremor or inability to sit still
fever, chills, sore throat, or flu-like symptoms
difficulty breathing or swallowing
severe skin rash or hives
yellowing of the skin or eyes
irregular heartbeat

What storage conditions are needed for this medicine?

Always store lisinopril at room temperature away from moisture and heat.

Remember to throw away any medication that is outdated or no longer needed and, if necessary, talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose


In the case of an overdose, call your local poison control center on 1-800-222-1222. However, if the victim has collapsed or is not breathing, please call the local emergency services immediately on 911.

Symptoms of overdose may include:

  • extreme dizziness
  • weakness
  • fainting
  • fatigue

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